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Amgen Jobs in Oakland – Scientist

Amgen

Job Description:

This role will be responsible for supporting PKPD-related and mathematical modeling activities in the PKDM space for drug discovery and development. The Scientist in this role will work directly with other PKDM stakeholders to apply quantitative solutions in the development of novel therapeutics through various activities including target/compound evaluation, design of preclinical studies, investigation of exposure-response relationships, execution of translational strategies, and influencing clinical study design.

Job Responsibilities:

  • Document and archive contributions including data analyses, mathematical models, summary presentations and reports to be shareable with other scientists and foster a collaborative environment
  • Devise and implement quantitative analysis and strategies to inform decision making in drug development by using mathematical modeling and quantitative pharmacology principles with a focus on mechanistic and translational modeling
  • Summarize and articulate salient findings, communicate conclusions back to project team representatives and cross-functional teams and actively participate in team discussions supporting decision making in drug development
  • Collaborate with project team representatives within PKDM and multi-disciplinary teams to generate key knowledge to inform these quantitative strategies
  • Build effective collaborations with peers and stakeholders within and outside the PKDM department including chemistry, biology, toxicology, biomarkers and protein scientists
  • Conduct hands-on work on fit-for-purpose mathematical models (PK-PD, PBPK) using specialized relevant modeling tools

Job Requirements:

  • Hands-on experience using Phoenix/WinNonLin, ADAPT, SimBiology/MATLAB, R, or relevant modeling software is required
  • Highly motivated, self-driven, can perform well both working independently and in team settings
  • Must have strong understanding of pharmacokinetic and pharmacodynamic principles
  • Critical thinking and demonstrated ability to communicate with team members across broad disciplines
  • High degree of flexibility with ability to adapt to different projects and teams
  • Doctorate (Ph.D.) in chemical or biomedical engineering; applied mathematics; quantitative pharmaceutical sciences or a related field with 0-3 years of experience in drug discovery and development
  • Excellent oral and written communication skills

Job Details:

Company: Amgen

Vacancy Type:  Full Time

Job Location: Oakland, CA, US

Application Deadline: N/A

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